منابع مشابه
Pathways of glyceride glycerol synthesis.
Isolated rat liver parenchymal cells were incubated for various periods with [U-(14)C,2-(3)H]glycerol and the radioisotopic yields in the major products were determined, as well as the (3)H/(14)C ratios in glyceride glycerol and intracellular glycerol phosphate. Under the conditions used (0.1mm-glycerol+10mm-l-lactate or 10mm-glycerol as substrates), only small differences were found between th...
متن کاملThe metabolism of glyceride-glycerol.
Various aspects of glycerol metabolism have been extensively investigated, both in vivo and in vitro, with the aid of isotopic glycerol. Experiments in vivo on the incorporation of C14-glycerol into glycogen and various body lipides, as well as its oxidation to C1402 have been reported (l-3). The metabolism of Ci4-glycerol by liver in vitro (4) and glycogen synthesis from deuterium-labeled glyc...
متن کاملSynthesis in Vitro of Glyceride-glycerol by the Liver of Normal and Pancreatectomized Rats.
In a preliminary study of lipogenesis in vitro in livers of diabetic rats, it was observed that insulin lack did not affect the incorporation of fructoseJ4C into total lipid even though it markedly reduced fatty acid synthesis.1 Since the difference in 1% content between total lipid and fatty acid could represent 14C label in glyceride-glycerol, this finding suggested that glyceride-glycerol sy...
متن کاملGlyceroneogenesis and the supply of glycerol-3-phosphate for glyceride-glycerol synthesis in liver slices of fasted and diabetic rats.
The pathways of glycerol-3-phosphate (G3P) generation for glyceride synthesis were examined in precision-cut liver slices of fasted and diabetic rats. The incorporation of 5 mM [U-(14)C]glucose into glyceride-glycerol, used to evaluate G3P generation via glycolysis, was reduced by approximately 26-36% in liver slices of fasted and diabetic rats. The glycolytic flux was reduced by approximately ...
متن کاملControl of hepatic glyceride synthesis.
Role of the liver in glyceride metabolism In mammals, there are three major forms of circulating lipid or lipid-related fuel, free fatty acid (FFA), triglyceride (TG) and ketone bodies. The liver utilizes FFA, and releases T G and ketone bodies. Constituents of the pool of carbohydrate plus amino acids can undergo net conversion to acetyl residues and then to fatty acids (FA) (FA synthesis ‘de ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1974
ISSN: 0306-3283
DOI: 10.1042/bj1400249